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There was also a negative relationship between the total sulphate and glucuronide conjugates and the other metabolites, indicating that if the estrogens are not biotransformed, they are converted into sulphate or glucuronide conjugates, which agrees with the current understanding of estrogen biotransformation

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doi:10.1093/qjmed/90.3.213

Moreover, KD is not suitable for all diseases and even the ratio difference in the KD formula may lead to unexpected therapeutic outcomes, thus increasing the need for precision nutrition and nutrigenomics research

However, always screen for G6PD deficiency before administering high-dose vitamin C