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3.4.2 Cytokines/chemokines/transcription factors BTZ markedly upregulates TNF- expression in DRG neurons, activates TNFR1 and TNFR2 co-receptors, sensitizes nociceptive neurons, and mediates mechanical allodynia (Li et al., 2016)

The docking results suggest that the positively charged guanidinium group of Arg240 interacts strongly with the carboxylate group of L -tyrosine and L -DOPA, whereas the amine group (which is predominantly positively charged at the investigated pH) of the other two substrates is electrostatically repelled (Fig

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cDNA cloning and tissue-specific expression of a novel basic helix-loop-helix/PAS factor (Arnt2) with close sequence similarity to the Aryl hydrocarbon receptor nuclear translocator (Arnt)

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