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Further studies in aptamer-based immunotherapy should be able to overcome the present obstacles and offer new effective treatments with less side effects to patients affected by solid tumors and beyond

Persistent unexplained elevation alongside an abnormal CBC or differential, constitutional symptoms such as unexplained weight loss, night sweats, or persistent fever, or organ-specific findings all raise the need for referral

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More recently, ventral abdominal subcutaneous injections have been used because of the perceived relative ease of tumor removal without the need for amputation