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The identification of alpha-synuclein as the first parkinson disease gene

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Historically, the crocodilian industry has prioritized skin processing, leaving by-products such as meat, fat, bone, and bloodcomprising nearly 90% of the animals masslargely underutilized and primarily consumed as food

However, these two studies were retracted, partly due to the negative results of a large scale RCT, namely the TRIPSS study

Oxidative stress arises from an imbalance between the production of reactive oxygen species (ROS) and the antioxidant defense system, disrupting redox homeostasis and promoting damaging effects on the structural and functional aspects of the cell [9]

Therefore, we optimized our search strategy by categorizing the botanical drugs into metabolites such as flavonoids, polyphenols, terpenoids, alkaloids, saponins, and anthraquinones, and combining these with more specific keywords like ALD, alcohol-related liver disease, alcoholic liver disease, oxidative stress, and ROS to improve the search accuracy