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doi: 10.1128/Spectrum.00223-21

220 For instance, Nivolumab, a human antiPD1 monoclonal antibody, reactivates the antitumour activity of suppressed effector Tcells

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4.2 Metformin interferes with energy metabolism of liver cancer cells The impact of metformin on tumor energy metabolism may be what causes it to have antitumor properties