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The tissue specimens were fixed in buffered formalin (pH 7.4), for 24 h, dehydrated, and embedded in paraffin wax

For example, one study developed a prognostic model based on ferroptosis-related genes using RNA-seq data from NSCLC patients, revealing that patients in the high-risk group had significantly lower overall survival compared to those in the low-risk group ( These findings indicate that ferroptosis-related genes not only play a pivotal role in the initiation and progression of lung cancer but also have potential clinical applications, providing a foundation for the development of personalized treatment strategies

Long non-coding RNA NEAT1 inhibits autophagy by activating AMPK, which indirectly mediates the phosphorylation of downstream mTOR protein [135]

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