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Mostofa, M

The canonical pathway is primarily triggered by MSU crystals through NLRP3 inflammasome activation and caspase-1 signaling, whereas the non-canonical pathway is mediated by caspase-4/5 in humans (caspase-11 in mice) in response to intracellular LPS

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Targeting lactylation epitopes in combination with existing immunotherapies may hold clinical translation potential

Plasmodium infection inhibits tumor angiogenesis through effects on tumor-associated macrophages in a murine implanted hepatoma model

The Contribution of Homocysteine Metabolism Disruption to Endothelial Dysfunction: State-of-the-Art