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This approach leads to selective oligodendrocyte stress and death, resulting in acute demyelination of distinct brain subregions, extensive microglial activation and astrocytic proliferation, a breakdown of the axonal transport mechanisms (Rhling, 2019), and, in more chronic models, overt axonal damage (Lindner, 2009)

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doi: 10.3390/molecules25010003 91 BukariBSamarasingheRMNoibanchongJShigdarSL

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The usual "other issues" seem to be low folate, low ferritin, low vitamin D and thyroid problems -and so all these should be checked, treated if necessary and monitored

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