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The NAD(+)/Sirtuin pathway modulates longevity through activation of mitochondrial UPR and FOXO signaling

R Muhammad, MD, P Fernhoff, MD, Dept of Pediatrics, Emory Univ, Atlanta, Georgia

There are other alternative forms for B-12 administration which includes monthly intramuscular injection, sublingual (under the tongue) liquids or sprays, or nasal spray which more adequately enable absorption. (Source) The current ASMBS recommendations for VSG (which are summarized here) list a B-complex vitamin (which includes B-12) as optional but doesnt elaborate on how it should be taken

In most cases, simply reducing the amount that you take is usually enough to reduce the symptoms

So, getting enough B12 is important for overall health

Pharmaceutical prospects of bee products: special focus on anticancer, antibacterial, antiviral, and antiparasitic properties