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Can Skin Whitening Be Permanent

As aforementioned, most studies have been conducted in vitro or in vivo

10.1021/tx060234h 129 McGillM

MSC shows its immunosuppressive effect by directly or indirectly induces the polarization of CD4 + T cells to Tregs, and inhibits the proliferation of B cells and the production of antibodies

While the majority of patients respond favorably to topical corticosteroids (135), calcineurin inhibitors (136), and immunosuppressants (137), these treatments are often associated with significant adverse effects during long-term use (138)