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no RCT has directly compared fasted morning versus other timing windows for subcutaneous AOD-9604.) Practical injection protocol: Dose: 250 mcg to start

Cross-species emesis-blocking confirmed in musk shrew (Geisler/Borner 2020) and beagle + ferret (Takeda WO 2018/181864 A1)

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Once exposed to room temperature for extended periods, the vial should not be returned to refrigerated storage and used beyond the 21-day window

Beyond this, hCG has been shown to stimulate VEGF production significantly in endometrial tissue, suggesting a role in the control of endometrial vascularisation and placentation