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They also play important roles in preserving spermatogonial homeostasis and guaranteeing the equilibrium between proliferation and differentiation in the germ cell population [66], miR-224, which targets DMRT1 in mice to encourage SSC self-renewal [66], The commencement of spermatogonial meiosis has been linked to miR-202-3p, whereas miR-10b targets the transcription factor KLF4 in mice to promote spermatogonial SSC self-renewal, which affects the equilibrium between germ cell maintenance and differentiation [67, 68]

Response rate and safety of a neoadjuvant pertuzumab, atezolizumab, docetaxel, and trastuzumab regimen for patients with ERBB2-positive stage II/III breast cancer: the neo-PATH phase 2 nonrandomized clinical trial

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PMID: 40342326 bioRxiv2025 Oct 2

Overall, the regulation of the NF-B signaling pathway by zinc involves a complex series of molecular events spanning from the activation of upstream signaling molecules to the regulation of gene expression in the nucleus

And when they did tick surveys, between 80% and 100% of the ticks that they analyzed contained Lyme disease