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Nitrosoureas are a group of alkylating agents that can cross the bloodbrain barrier (BBB) and are cell phase non-specific and lipid soluble [38]

Numerous methods rely on classical cheminformatics and computer-aided drug discovery tools to predict the biological activity of drugs

The plant bioresource needs to be screened appropriately for various therapeutic activities for the discovery of new drugs

Finally, the processed protein samples were detected by Western blot

( mRNA quantification by quantitative real-time PCR (qRT-PCR) Total RNA was isolated using QIAzol-Reagent (Qiagen, Germany), based on modified Chomczyski & Sacchis method (Chomczynski and Sacchi, 2006), following the manufacturers protocol

PHOTACs enable optical control of protein degradation