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[1] Glutathione peroxidase and the disposal of peroxides Glutathione does much of its most important work not alone but as the substrate for glutathione peroxidase (GPx) , a family of (mostly selenium-dependent) enzymes that reduce hydrogen peroxide and lipid peroxides to water and harmless alcohols

Aging chronically reduces the cytoplasmic [NAD + ]/[NADH] in some tissues due to a decrease in cytoplasmic [NAD + ] that decreases sirtuin activation

NAD+ supports mitochondrial activity, while glutathione helps control oxidative damage generated during energy production

The peptide anti-inflammatory action is not limited to any single tissue type

Zheng T, Schlosser S, Dao T, Hingorani R, Crispe I, Boyer J , Flavell R

Role of fat-soluble vitamins A and D in the pathogenesis of influenza: anew perspective