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10.1016/j.chembiol.2008.02.010 167 YangY.ChenJ.GaoQ.ShanX.WangJ.LvZ

The C129S mutant of PGRMC1 also interacted with endogenous PGRMC1 and EGFR (Supplementary Fig

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CBS indicates coomassie blue staining

Studies have also shown that disulfiram-copper (DSF-Cu) can inhibit aldehyde dehydrogenase (ALDH), targeting cancer stem cells, and therefore has a synergistic effect on the chemoresistance of tumor stem cells that affect sorafenib treatment outcomes (199)

Comparisons with previous in vivo studies with praziquantel suggests that these inhibitors outperform the drug of choice for schistosomiasis against juvenile worms