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HGF is the sole ligand for c-Met, and HGF binding with c-Met can lead to c-Met phosphorylation, which activates several intracellular signaling pathways, including MAPK, STAT3, and PI3K/AKT

Sweeney et al., 2018, 2020

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Preliminary cardiac studies have also explored the use of recombinant human T4 following severe ST-segment elevation myocardial infarctions (STEMI), with early pilot data suggesting the intervention is feasible, safe, and potentially capable of improving left ventricular ejection fractions by more than 50% in specific cohorts six months post-infarction

It wrote an entire piece about a health controversy without quoting a single physician, researcher, or patient who has had a positive experience with the compounds

In fact, the study concluded that all of the rats treated showed significant improvement in being able to move their tails after paralysis