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1 Introduction Myelodysplastic neoplasms (MDS) are a group of clonal myeloid stem and progenitor cell disorders, characterized by bone marrow (BM) failure resulting in cytopenias and a propensity to progress to acute myeloid leukemia (AML) ( Monocytes fulfill a crucial role in the immune system and their presence in MDS has been correlated to leukemic transformation ( To date, reviews on TM expression comprise mostly endothelial-TM ( 2 Monocyte biology in healthy, aging individuals 2.1 Monocyte ontogeny, subsets, and heterogeneity Monocytes are named after their morphology: cells with a single nucleus

Longitudinal tracking of ALK-positive lung cancer from plasma using circulating-tumor RNA and circulating-tumor DNA in the BRIGHTSTAR clinical trial 41(Suppl 16), 2023

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Signs of degradation include cloudiness, visible particles, unusual color changes, or unusual odor

Blood 59(2):216-25, 1982