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If chemotherapy interruption is not possible, then the addition of pharmacologic and/or nonpharmacologic therapies is common

When DAO levels are insufficient, dietary histamine accumulates in the bloodstream, leading to a state of histamine intolerance that exacerbates systemic inflammation

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In the presence of bioactive iron, the PM-PLs can be converted to PL-hydroperoxide (PLOOH) through enzymatic or nonenzymatic lipid peroxidation mechanisms