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Yes, folate is essential for cell division and DNA synthesis

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Among significantly upregulated genes (Dataset EV1) we found known factors upregulated by brain injury such as the JNK target mmp1 and several GO terms related to redox-dependent processes (Fig EV1A)

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Its well known that having a homozygous mutation is more likely to cause health problems and having a heterozygous mutation is unlikely to cause issues

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