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Despite a substantial body of evidence from animal and clinical studies supporting the hypothesis 5,6,7,8,9,10 and the potential efficacy of SSRIs 11 , their clinical use remains a subject of controversy

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For example, DTCs of gastric cancer express various stem cell markers, such as LGR5, TROY and ALDH1A1, and ALDH1A1 can promote the formation of DTC of acute myeloid leukemia cells through up-regulating mTOR (20)

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Ionic mechanisms of neuronal excitation by inhibitory GABAA receptors