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doi:10.1136/jmg.2009.073015

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4.4 Efficacy mechanism of gene drug therapy At present, some gene drugs can effectively treat BLED by enhancing cellular antioxidant capacity, regulating endoplasmic reticulum stress, and fundamentally reducing the damage of blue light to eye cells, thereby achieving good therapeutic effects

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Taketa T, Correa AM, Suzuki A, Blum MA, Lee JH, Welsh J, Lin SH, Maru DM, Erasmus JJ, Bhutani MS, Weston B, Rice DC, Swisher S , Hofstetter WL, Ajani JA