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Journal of Molecular Neuroscience 44: 611

Fe 2+ , free iron ions, forms an unstable iron pool (LIP) in cells, which is transferred to mitochondria and participates in the formation of iron-dependent protein complexes, iron-sulfur clusters, heme, and other metabolic processes

72 Intracranial pathological changes of microangiopathy include endothelial dysfunction, platelet aggregation impairment, and increased inflammation

Proc Natl Acad Sci U S A 115:1164311648

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demonstrated the action of DATS against motor neuron-like NSC34 cells overexpressing TDP-43, a pathological and biochemical marker for ALS