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safety monitored through hormone panels and metabolic assessments

revealed that individuals with elevated STAT4 and PD-L1 levels experienced reduced overall survival (OS) compared to those with lower STAT4 and PD-L1 levels, indicating the crucial role of the MET/STAT4/PD-L1 pathway in facilitating glioma immune evasion, which is associated with a less favorable outlook in primary glioma cases [67]