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J Cell Mol Res (2011) 3(2):5765

As a cornerstone of future IBD care, personalized therapy integrates multi-omic information with emerging technologies to achieve precise management and individualized intervention

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In astrocytes, GlialCAM and MLC1 assemble into a functional unit, interacting with Na + K + ATPase, SLC ionic transporters, K ir 4.1 channels, connexins, AQP-4 water channels, volume-regulated anion channels (VRAC) and transient receptor potential vanilloid 4 channel (TRPV4), and are also associated with the dystrophinglycoprotein complex regulating endfeet channels and transporters 339,340,341

It is well documented that the processes of cryopreservation and transplantation induce significant oxidative stress in ovarian tissue, a phenomenon closely paralleling the impact of ROS observed in cryopreserved oocytes (69, 70)

Samples were then evaporated to dryness in Speed vac and resuspended in 500 l Velos buffer A (95% H 2 O, 5% CH 3 CN, 0.1% FA) with additional 20 l of 20% FA to ensure the samples were acidic