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Once present in the cell, the efficiency of homologous recombination is such that homologous recombination occurs between the various vectors

Studies have shown that phospholipase A 2 (PLA 2 ) catalyses the hydrolysis of sn-2 acyl ester bonds in phospholipids to produce active metabolites, including lysophospholipids and AA, which alter various cell functions (Turolo et al., 2021)

40 Partial biotinidase deficiency, defined as 1030% of mean normal serum activity, initially was considered a variant without clinical consequences

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On one hand, ERS can induce apoptosis via CHOP-mediated Bcl-2 family imbalance and JNK pathway activation [6,7,8,9], trigger pyroptosis through NLRP3 inflammasome activation [10], or promote ferroptosis via the ATF4CHAC1 axis [11, 12]

After 72 h, the cells were harvested and lysed with 2.0 mL of 1.0% Triton X-100 in TBS (~10 10 6 cells/mL)