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One proposed mechanism involves the body's stress response

Moreover, the LIF protein has been shown to increase the transcription of HGF , which encodes an important neuroprotective molecule 36

This can cause local tissue damage, though with just sterile water the damage is primarily due to the hypo-osmolar effect (cells swelling with water)

Similarly, the healing of spinal cord injured rats through BPC 157 therapy is interesting, as very early, upon injury, there is a decrease of hematoma amid strongly elevated NOS-1, NOS-2, and NOS-3 gene expression (the mRNA expression studies) [170]

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The family faced a daunting set of choices: two medications, both with a list of potential side effects, but little guidance on alternative treatments