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The risk-based approach for evaluating newly obtained HBM data is challenging and requires information on relationships between biomarker concentrations and mycotoxin intake from human and/or animal studies or toxicokinetic modelling, as well as toxicity profiles including mode of action

Baena explains that melatonin is a hormone released by the pineal gland in the brain

10.1016/j.actbio.2015.09.039 336 ZukP

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The intervention group received a single injection of 1 mL/kg of 75% hypertonic glucose directly into the facet joints (L1-L2, L5-S1) [64]