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Compound 18 significantly reduced the levels of TNF-, IL-6, COX-2, and iNOS in LPS-stimulated BV-2 microglial cells

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"Despite statements on your product labeling marketing your products for laboratory research purposes only and not for human consumption, medical use or veterinary use, evidence obtained from your website establishes that your products are intended to be drugs for human use," the agency wrote

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The NICE Guideline NG239 (2024) and the AAFP clinical review both support this approach

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