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The physiological role of -synuclein and its relationship to Parkinsons disease

10.1016/j.actbio.2021.03.002 76 KimJ.LiS.ZhangS.WangJ

On the contrary, EECGL beneficially blunted the pro-inflammatory factors with boosted anti-inflammatory factors to attenuate HM induced inflammation via inhibition of NF-kB (p65) signaling pathway

In other words, they can reduce the spontaneous firing of nerves, which may, in turn, reduce the tinnitus

In summary, dysbiosis might contribute to neurodegeneration by disrupting metabolic homeostasis reducing beneficial metabolites (SCFAs, vitamins) and increasing potentially neurotoxic ones (e.g

In malignancy, tumor suppressor genes are silenced, therefore the most commonly known epigenetic aberration found in cancers is the hypermethylation of promoters which is responsible for silencing certain genes