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This structure-based recognition, rather than sequence-based recognition, allows broader flexibility in the protein sequence between SUMO and the protein of interest

Conjugation with glutathione receptors renders toxic substances more soluble, and therefore more readily exocytosed from the cell

The effect of amlodipine is comparable to that of standard agents with proven antiglycation (aminoguanidine) or antioxidant (N-acetylcysteine

Sotgiu S, Zanda B, Marchetti B, Fois ML, Arru G, Pes GM, et al

Lastly, the models were trained and tested on American and Caucasian-skewed cohorts, and future studies should assess the generalizability of the findings in more ethnically and geographically diverse populations