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Gastrointestinal complaints are observed in 9% to 91% of individuals with ASD [20]

When 5GABA-A receptor PAM, MP-III-022 was used in rats in the VPA model, an increase in mRNA level of KCC2 was observed only in females treated with a dose of 1 mg/kg, while the mRNA level of Gabra5 and Nkcc1 remained unchanged across doses and animal sexes [58]

Sokolov et al., 2021)

Lorenz for comments on the manuscript

10.1053/j.gastro.2013.11.034 102

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