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Adenovirus-mediated overexpression of CD36 enhances hepatic fatty acid uptake and fat accumulation [22], while liver-specific knockout of CD36 decreases hepatic lipid levels in both genetic and diet-induced steatosis [23]

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Allopurinol, a prevalent treatment for symptomatic HUA or gout, has been demonstrated to mitigate T cell activation following CD3 and CD28 antigen stimulation