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No antiviral agents to manage DENV infections are yet licensed and the clinical benefit of the available tetravalent DENV vaccines, Dengvaxia and Qdenga, are limited by safety concerns and inconsistent long-term efficacy across the four DENV serotypes (Sridhar et al., 2018)

WADAs S0 classification covers any pharmacological substance not approved for human use by a governmental health authority , meaning a positive test could result in sanctions regardless of whether the compound is directly listed

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Loss of colour over time can indicate degradation or copper dissociation, so storage protocols matter

ELF values close to 1 (red regions) indicate highly localized electron pairs, whereas lower values (blue regions) correspond to delocalized or depleted electron density

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