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Need to make the - NH 2 leave, but need to convert it into a good leaving group first byprotonation

Approach Phase 2b trial arm Duration 24 weeks Review Point Week 12 and 24 Notes METAOD006 (OPTIONS) used 24 weeks at oral doses 0.25, 0.5, or 1 mg/day in 502 obese adults

It works by reducing appetite and increasing feelings of fullness, which can lead to decreased food intake and subsequent weight reduction

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For I have 3 three questions: 1) Have you seen a way to equate dosages between oral form and subcutaneous injection to help determine what dosages correspond to each form