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By administering it intratympanicly, as near to the round window as possible, the inner ears bioavailability is enhanced, and the negative consequences of systemic administration are avoided (Fujimoto and Yamasoba 2019)

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Moreover, within the patient group, those who exhibited the specific POTS pattern during tilt-table testing had significantly lower B12 levels than those who did not

Briefly, 100 L of a 1 mg mL 1 sterile mucin solution dissolved in a buffer saline (PBS, pH 7.4) was aliquoted into 96-well microtiters (Sarstedt, Germany) and incubated overnight at 4C