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Supplementary information Raw gel images for all western blots and replicates

Based on our experience, the plasma or serum sample has good stability when stored at -20 (more than 6 months) and pooled plasma samples as well as commercially available quality control sera can be used as in-house reference standard for cholinesterase activity after analyzing BChE by the proposed method

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For H&E staining, tissue sections were deparaffinized, rehydrated, and stained with Hematoxylin (H3136, Sigma, Germany) for 5 min followed by Eosin (E4009, Sigma, Germany) for 2 min

Many patients start with CJC/Ipa alone and add a second peptide at month 3-4 if goals warrant it