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Unesterified fatty acids also destabilize lysosomes leading to activation of NF-B-dependent tumor necrosis factor (TNF-) expression which potentiates lipotoxicity-driven inflammation (122)

Atorvastatin induces mitochondria-dependent ferroptosis the modulation of Nrf2-xCT/GPx4 axis

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Clinically, dobutamine is used for short-term inotropic support in cardiac decompensation and perioperative cardiac surgery settings

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