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The levels of telomeric DNA in samples were quantified using qPCR, the reference gene used was the single-copy gene 36B4, with primers for both telomeric and 36B4 sequences outlined in Table 1

The prolonged accumulation of low-density lipoprotein can induce an oxidative stress response (159)

Certain conditions may blunt or impede therapeutic response to methylcobalamin therapy

High hemoglobin count can be visible in routine CBC tests

Rationale for metabolic state-driven as an approach for restoring susceptibility in multidrug-resistant pathogens Recent findings demonstrate that the local environment modulates bacterial drug uptake and other aspects of bacterial metabolism 10,11,16,17,18

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