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FIGURE 5 To further investigate the connection between elevated ROS levels and the action of antibiotics, we conducted experiments to inhibit ROS production using ascorbic acid (AA), a known antioxidant, alongside each antibiotic

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(6) nitric oxide increased by vagotomy in basal state and by sensory denervation and cholinergic blockade in basal state and during endotoxemia

Experimental NNMT inhibition with compounds such as 5-Amino-1MQ has been reported to correlate with: Reduced fat cell size and changes in fat mass in diet-induced models Shifts in metabolic efficiency and energy utilization Altered expression of glucose transporters (including GLUT4) in skeletal muscle and fat tissue Some studies have observed notable changes in body mass and adipose tissue over relatively short experimental periods without modifications in food intake

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Franzini et al., 2014)