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Taken together, the findings that increasing age is associated with higher risk of dysbiotic endometrium and that dysbiosis negatively impacts ART outcomes, suggests that adverse effects of an aged endometrium on reproduction may, at least in part, be attributed to microbiome changes

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In addition, the presence of CKD increased cardiovascular risk and mortality in patients with diabetes

The dynamic inflammatory tissue microenvironment: signality and disease therapy by biomaterials

Apart from the truncation at the N-terminus SnCE1 104-310 and the mutant SnCE1 104-310 C256A recapitulate all effects observed for the longer SnCE1 construct, i.e., SnCE1 74-310