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Mice rendered incapable of oxidizing the ketone body 3-HB in the heart exhibits worsened heart failure compared with WT controls

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Placebo or LC was given at a dose of 9 g/day intravenously for the first 5 days and then 6 g/day orally for the next 12 months

Since NAD+ is closely linked to vitamin B3, these supplements are generally safer than the botanical blends in nootropics, though they arent necessarily less expensive, depending on the brand you choose