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Therefore, ubiquitination is not only important for protein degradation, but is also implicated in non-proteolytic functions, such as endocytosis, protein-protein interaction, intracellular trafficking, inflammatory signaling, autophagy, and DNA repair (Grabbe et al., 2011

Its also about the silent storm of oxidative stress and mitochondrial dysfunction that damages cells over time

10.1002/art.24140 120 PanH.HuangW.WangZ.RenF.LuoL.ZhouJ.et al (2021)

This strategy is commonly used in site-specific cross-linking with bis or tri-electrophilic linkers and has proven to be a powerful method for reinforcing protein secondary and tertiary structures 37,38

Effects of altering dietary fatty acid composition on prostaglandin synthesis and fertility