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[DOI] [PMC free article] [PubMed] [Google Scholar] Han, F

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The trial did not meet its efficacy endpoint, but tolerability was not the reason the program was discontinued

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Maintenance dosages typically mirror initial loading doses at 600-1,200 mg but with reduced frequency

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1 In support of this notion, ferroptosis has been functionally validated in cancer types with increased PL peroxidation, including hepatocellular carcinoma (HCC), 34 pancreatic ductal adenocarcinoma, 35 triple-negative breast cancer (TNBC), 36,37 and renal cell carcinoma

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