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Notably, in erythroid cells, caspase-3 activation does not guarantee apoptosis execution, since the transcriptional factor GATA-1 essential for erythropoiesis is protected from caspase-3 by HSP70 (heat shock protein 70)

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When this happens, cats may develop a deficiency, leading to symptoms like lethargy, loss of appetite, and even neurological issues

Their approach highlights how complex biological data can inform nanoparticle design for targeting neurodegenerative pathways

Retrieved from doi:10.1101/cshperspect.a005686

Without treatment, the infection may spread to the kidneys