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Primary aliphatic amines are metabolized via the same mechanism, where hydroxylation of the alpha-carbon occurs, followed by rearrangement to release ammonia, and this is termed de-amination (as opposed to N -dealkylation)

The phase separation of tau droplets into gel-like states before transitioning into cytotoxic fibrils that are associated with NDDs is also fueled by the dehydration of hydrophobic protein residues [266, 267]

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The core mechanism GHRH receptor activation followed by GH and IGF-1 signaling remains the same

4-9 (AD Little, Cambridge, MA, 1964)

Elghareeb MM, et al