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Dimensions: 6000 x 2340 px | 50.8 x 19.8 cm | 20 x 7.8 inches | 300dpi Date taken: 10 June 2017

In addition, the promotion of HDAC1 to SMAD7 ubiquitination [92, 93], thereby decreasing the half-life of the protein, is also observed, although the concrete mechanism remains unknown