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[6] Some studies have focused on the impact of the duration and doses of Figure 2

Levels decline with age, stress, alcohol, and poor diet

10.1007/s12035-017-0448-z 80 JayaprakashP.IsaevD.ShabbirW.LorkeD

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Because these enzymes are responsible for metabolizing a vast majority of pharmaceutical drugs, taking berberine can significantly elevate the blood concentrations of co-administered medications, potentially leading to dangerous toxicity