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10.1016/j.cell.2006.01.016 13

This article will briefly review the function of glutamine in the immune system, with emphasis on metabolic mechanisms, and the emerging role of glutamine in the brain glutamate/gamma-amino butyric acid cycle

In order to test a possible effect of intracellular glutathione synthesis, buthionine sulfoximine (BSO), a specific inhibitor of -glutamylcysteine synthetase, was used to block the first step of intracellular glutathione synthesis