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However, these models have not successfully recapitulated CD until recently, when Abadie and colleagues modified the DQ8-D d -IL-15tg model to overexpress IL-15 in intestinal epithelial cells under the villin promoter, resulting in the DQ8-D d -villin-IL-15tg model (Abadie et al, 2022

ACS Nano 2015, 9, 251259

Kawamoto et al., 2024

All laboratory values were within the reference range or were judged by the investigator not to be clinically relevant

Rights and permissions About this article Cite this article Shin, M.D., Shukla, S., Chung, Y.H

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