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(2019, Dec 2)

Moreover, a direct targeting approach may stimulate the rapid release of bacterial endotoxins

We thus tried to investigate the potential for VRK2 phosphorylating Sec24C and found that the phosphorylation level of Sec24C was attenuated in VRK2-KO cells but elevated when restoring the expression of VRK2 (Fig

Heavy lysine-labeled samples were spiked with nonisotopic d- and l-lactyl lysine standards, and then analyzed in a Fusion Lumos Tribrid mass spectrometer equipped with a Dionex Ultimate 3000 nanoLC system (Thermo Fisher Scientific)

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Furthermore, the resulting superoxide increased cytosolic ROS and membrane lipid peroxidation of murine macrophage, and eventually caused fatal oxidative damage, which involves autophagy and ferroptosis but not apoptosis